Coats disease is a chronic, progressive disorder that affects the
retina, the light-sensitive nerve layer at the back of the eye. Coats
disease is an abnormal growth spurt of the small blood vessels
(capillaries) that nourish the retina. The fragile abnormal vessels
break and leak the clear serum part of the blood into the retina,
causing the retina to swell.
Coats disease usually affects children (especially boys) in the first
ten years of life, but it can also affect young adults. The condition
affects central vision, typically in only one eye. Severity can range
from mild vision loss to total retinal detachment and blindness. No
cause has yet been identified for Coats disease.
The leaking blood vessels can be treated with laser surgery or
cryotherapy (freezing). If the retina is detached, a vitrectomy to
replace the vitreous (the clear gel-like substance inside the eye) with
a gas bubble may be necessary to restore vision.